In this area, items are more patterned after DOTA, then WOW or other RPG's. In DOTA, you can have whatever combination of items in your inventory. Some do not work together, some are unique, but if you wanted to have 4 great axes when it is apparent that your hero is carrying around a staff, then so be it. There's quite a bit of supsension of disbelief since obviously DOTA creators are not able to code in each item in as a graphic, representation.
I'd like to see Demigod show the items with a graphic represenation (the advantage of making the game from scratch). However, if they do, they would need to consider limiting the items (2 gloves, 2 boots, 1 helm, 1 breastplate, 10 rings, etc) and re-working the system as Innociv has said.
Who knows, its too early to tell. The whole item system is subject to change.