I get a random hard crash during gameplay where the game freezes up. Animations in the UI still continue but the graphics themselves stop working. If you zoom in on the map you can hear the sound of the waterfalls too so I guess this means the sound engine is still running. You can Alt+F4 out of the game, or access the F10 menu without a problem and can return to the main menu and start another game if you wish.
When I crash, going through the runtime log I find I have this error:
INFO: Sim crashed hard in DoSimBeat(): vector<T> too long
I also regularly have these errors:
INFO: CONTENT ERROR: No valid model specified for unit: buildseed
WARNING: Unable to locate mesh blueprint [/units/misc/buildseed_mesh]!
INFO: CONTENT ERROR: No valid model specified for unit: buildseed
INFO: Search failed due to invalid start or end nodes in the graph tree
Which might be related, I'm unsure. I usually crash when QoT is doing something fancy.
Update: Hmm, played a couple of games without the QoT and the game doesn't seem to crash. Looks like there's something odd in the QoT code.