I just got two Western Digital 1 TB My Book drives, one the Essential Edition (USB only, write transfer rate about 25.8 GB/s) the other a Home Edition (eSATA, write transfer rate about 48.4 GB/s). I use them both strictly for backups and the drives are always on.
These things run HOT (case is passively cooled, no fans), often going up to 48º C (with 19/20º C ambient) just sitting there idle! With temperatures like these, it's no wonder My Books are getting a bad rep: the drives and interface electronics must simply fry during Summer.
I solved the excessive temperature problem by purchasing a relatively cheap Nox Sirocco notebook cooler with 3 fans: placed the two My Books on top and tapped shut the grill holes around them, forcing the cold air propelled by the fans to exit via the hard drive enclosures. Result: both My Books now run at 28º C, which is even lower than the temperatures of some of my internal hard drives.
Also, if you choose eSATA, be warned that these drives do NOT include an eSATA cable, you will have to purchase one separately. Furthermore, with some cables the metal part of the connector is too short and seems to plug into the drive, but isn't really making full contact. This is a common problem, and if it happens to you and the drive is not recognized by Windows, cut 3-4 mm of the plastic around the cable's connector to expose a bit more metal - that worked for me.
Another common issue, at least in eSATA mode, is that these drives are hard-coded to sleep after being idle for 10 minutes. Unfortunately they then take too long to spin up and end up being hard dismounted by Windows (i.e. they disappear from My Computer). Only way to get them back is by rebooting the system. I solved this issue by making a small applet that copies - then deletes - itself to the drive every 5 minutes, thus reseting the idle timer and preventing the drive from automatically spinning down.