sure:
AMD Athlon X2 4200+ (2.2Ghz dual core... ancient)
2GB Ram
Nvida 260GTX video (896MB)
SoundBlaster Audigy 2 sound
Windows XP sp3
Dell 1600x1200 LCD display
I'm running at 1600x1200, with most settings either High or Medium, with AA off and Vsync off. Dunno the FPS, but it looks and plays fine. I'll probably bite the bullet and upgrade to an i7 system soon 