I tend to like to use QoT as a support assassin.
QoT is a very different demigod to play. I use her plenty and have a lot of fun out lasting my opponent and pushing them off my lanes. Normally she can't kill another DG by herself, but you can easily make them retreat and still have everything you need to stay for another round or two of fights. All of your AoEs have HUGE range as well. So you can easily kill entire waves of creeps and hit every DG nearby.
She does require a lot of mana to keep in the fight though. You might need 2 or even 3 mana helms if you're really active with her. But the lack of extra HP items isn't as bad since you can switch to using shield.
Her skills don't do a huge amount of damage to any single target, but for each additional target you hit with your AoEs, you can consider you skill multiplied.
Early game this support assassin I play tends to be long lasting but very weak due to low mana. Once I get some more mana and level 5 I become useful. And at level 10 you basically max out your normal skill damage. However, from then on you will need to rely more on creeps and other players. Keep in mind that by then your spike wave will be slowing for 20% at a huge range and your ground spikes will reduce 1500 armor on everyone hit. Just use that while a wave of creeps is beating on a tower or a DG and they'll normally take double damage.
Another big thing is being able to change forms while moving. If you aren't attacking and you are missing any mana or hp, then switch to closed mode for the extra regen and toss a shield on you just in case you run into trouble.
I've killed a fully leveled citadel at full hp with just 1 wave of creeps and my ground spikes in 10-15 seconds.