Hey Brad,
this is would be a real business improvement, if you would mod your emails for the target regions.
I for example are more or less p..... off this weekend, because I wanted to buy Witcher and X-Com Bundle (the TOP ad this weekend) and can not buy both of them, because I am in Western Europe (Dont know if there are more regional problems, I had enough at the second try).
I know this is at least at the bigger chunk of this problem is a publisher choice, but as a customer I react as described above - and avoid looking at ads from impulse. Steam is at least cleverer in the way not pushing me ads I cannot buy - even if they have the same regional problem.
The whole digital distribution and marketing is about customizing the ads and the product and at least the big regional modification should be made by now. Shouldnt cost too much, but works hell in customer satisfaction.
Best
yti