i think it could work on a console. Casting spells could automatically assign targets and just left-shoulder or right-shoulder target quickly, AoE spells can move rather quickly with the Analog sticks and most spells can't be cast that far from DG (except for Reg's Snipe, but that is a quick right/left-shoulder press away).
General DG would be a pain to control though; I'm imagining the DPD for Minions Only, Minions+DG, and a DG select scheme. And since minions don't have spells or clickable abilities beyond "attack" and "go here", they could also be shoulder-button controlled:e.g., Press Dpad DOWN (Minions Only), Press and HOLD right-shoulder to select destination, move left analog stick to chose, release right-shoulder to confirm location.