If you mean that you want a build focused mainly on Melee (hitting) and doing Big Damage, then you want to put points into the following skills every time you get a chance (and ignore the people who tell you, "...but max out Venomous Spit!". Believe it or not, Unclean Beast can do just fine without them.)
My melee build in the past has looked like this (and it requires some serious gold and a very good Favor item to REALLY shine, but when you can manage this...no one will want to let you get within a few feet of them, trust me!).
** Start with ONE skill point in Venomous Spit (This is the ONLY point I put in Spit for this build, for early game harassing and finsihing off fleeing Demigods).
** When it's available, put ONE skill point in Foul Grasp (I use it for stuns/interrupts only).
After that, *every time you get the chance*, put a point into whichever of these is available to you:
A) Inner Beast (Passive movement and attack speed bonus).
B ) Bestial Wrath (Activate for a short but hefty boost to Weapon Damage).
C) Base stats (the gold circle with the big white + at the bottom of your screen...passive Weapon Damage and other bonuses). If you have a choice between A), B ), or C)...choose A) or B ). When you can't upgrade those because they are not available, go for C).
** Once you have A) and B ) only 1 point away from Maxed Out, if C) is lagging behind....keep dumping points into it until it is also nearly maxed out.
This type of build gives you very nasty attack speed, movement speed, and weapon damage bonuses from skillpoints only. Add in the bonus from using Bestial Wrath before every fight, and you've already got a pretty nasty melee Demigod. Now comes the trickier part; Items to *really* make this guy (as the game commentator says) "GODLIKE!"
FAVOR ITEM: Furious Blades (+250 HP, 5% passive bonus to attack speed, AND a 15% chance to proc a 30% bonus to attack speed...and it procs often!)
A) 2nd set of gloves (5% attack Speed) early on.
B ) Plenor Battlecrown (You need this to increase your mana pool early on).
C) Heart of Life. I cannot overstate this one enough; Heart. Of. Life. It costs 4250 gold. You might have trouble in the early part of the game resisting the urge to buy OTHER things, but fight it. Save up for the HoL. Being able to turn from a fight, run away a bit and click the HoL to rapidly regen ALL your HitPoints and ALL your Mana is vital- not just to the UB but to all DGs if you ask me.
D) Hauberk of Life: Extra HP and HP regen.
E) Wyrmskin gloves (+15 weapon damage and a proc for extra damage over time...I believe).
F) ARTIFACT: Mageslayer (I think it's 25% attack speed bonus and a big boost to weapon damage).
G) ARTIFACT: Orb of Storms (another 25% or 30% to attack speed, plus a clickable 500 damage AoE effect).
I'll tell you this, right now; with this particular build (it will still work without the Furious Blades favor item, but takes a bit more finesse), you can basically walk up to a Tower and melee it down before the enemy even finishes hearing the "Our defenses are under attack" message. Fighting enemy Demigods really is a lot of fun when they expect you to Spit on them and instead you hit Bestial Wrath (UB roars) and walk right up to them to beat them down.
Give it a whirl; she's nasty. 